Dr Gabriele Schweikert, a researcher on the College of Dundee’s Faculty of Life Sciences has acquired a £1.6 million Future Leaders Fellowship award from UK Analysis and Innovation (UKRI) to develop machine studying instruments for higher understanding of molecular processes in dwelling cells and the way these go flawed in illnesses.
Working with Professor Tom Owen-Hughes, Head of the Gene Regulation and Expression Unit, on improvement of particular knowledge evaluation instruments to raised perceive epigenetic regulation of gene expression, she’s going to construct a group within the Division of Computational Biology with the required interdisciplinary competence to maximise the potential of machine studying in scientific analysis.
“At present few individuals are outfitted to deal with the challenges that come up within the interface between superior computational biology and wet-lab biology,” stated Dr Schweikert.
“The fast progress in machine studying know-how in addition to in experimental excessive throughput measurements, make it doable to search out hidden patterns in giant, advanced knowledge units. These patterns can then be used to make predictions in comparable circumstances that haven’t but been noticed.
“Nonetheless, many questions that encourage researchers within the biomedical sciences are concerning the underlying causes of the observations. Whereas algorithmic instruments can be found to deal with these questions as effectively, they aren’t extensively utilized in observe. In most situations, causes can’t be computed from knowledge alone, as they require extra information of the data-generating course of.”
Dr Schweikert initially educated as a physicist, however took an interest within the organic sciences early in her undergraduate research. Throughout an interdisciplinary PhD on the Max Planck campus in Germany, she developed new computational methods for DNA sequence evaluation. She began her personal analysis group on computational epigenomics at Dundee final yr and likewise holds an affiliation with the Cyber Valley Initiative, Germany, one in every of prime Europe’s centres for machine studying with a specific energy in causal inference.